Just Gene Therapy is a not for profit organisation established to raise funds for gene therapy for cystic fibrosis.

University of Oxford

The UK CF Gene Therapy Consortium Strategy Group representatives from the University of Oxford are:

Dr Deborah Gill

Dr Deborah Gill is a translational scientist with over 20 years of experience in the field of gene therapy.

Deborah undertook a PhD at the University of Warwick where she discovered the defining member of the ABC Superfamily of proteins, which was reported in Nature. Following post-doctoral work she became an Assistant Scientist at the Weatherall Institute of Molecular Medicine in Oxford, undertaking two clinical trials to evaluate non-viral gene therapy for cystic fibrosis (CF) in the mid-1990s. She is now a Research Lecturer at the University of Oxford and Co-Director of the Gene Medicine Research Group, focused on translating research into lung therapeutics.

As part of the UK Gene Therapy Consortium's clinical programme Deborah is responsible for the manufacture and procurement of the gene therapy product for clinical trials.

Dr Stephen Hyde

Dr Stephen Hyde has a DPhil in Biochemistry from the University of Oxford where he studied the structure and function of ABC proteins, including the protein responsible for cystic fibrosis. During post-doctoral research at Oxford Stephen was the first to demonstrate that gene transfer could correct the CF defect in transgenic mice. This led to an extensive pre-clinical and clinical programme of gene therapy. He has acted as a specialist advisor on the clinical safety of gene therapy vectors to both the Department of Health's Gene Therapy Advisory Committee and the Committee on the Safety of Medicines, and has advised the Department of Health's National Translational Cancer Research Network on the procurement of gene transfer vectors.

Stephen is now a Research Lecturer at Oxford University and co-directs the Gene Medicine Research Group developing gene transfer vectors for clinical application and leads on Regulatory Affairs within the UK Cystic Fibrosis Gene Therapy Consortium.

 

 

 

Dr Deborah Gill

 

Dr Stephen Hyde
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